CLOTRILIN 100 mg VAGINAL TABLET
Active Ingredient: Clotrimazole 100 mg
Family: Antifungal Agent (Imidazole Derivative)
Dosage Form: Vaginal Tablet / Vaginal Insert
Pharmacological Class: Topical Antifungal Agent
Product Description: CLOTRILIN 100 mg contains clotrimazole, a broad-spectrum antifungal agent used for the local treatment of vaginal yeast infections. It acts directly at the site of infection to inhibit fungal growth and help relieve symptoms associated with vulvovaginal candidiasis.
Indications: CLOTRILIN 100 mg is indicated for the treatment of vulvovaginal candidiasis caused by susceptible Candida species. It may help relieve vaginal itching, burning, irritation, redness, soreness, and abnormal discharge associated with fungal infection.
Mechanism of Action: Clotrimazole inhibits the synthesis of ergosterol, an essential component of the fungal cell membrane. This action alters membrane permeability and compromises fungal cell function, inhibiting fungal growth and, depending on the concentration and organism, potentially causing fungal cell death.
Clinical Benefits: CLOTRILIN delivers antifungal treatment directly to the affected vaginal area. It helps control susceptible Candida organisms, relieve infection-related discomfort, and support recovery from uncomplicated vaginal yeast infections. Its local route of administration generally results in low systemic absorption.
Key Benefits: Targeted local antifungal action; relief from itching, burning, and irritation; convenient vaginal administration; and effective treatment of susceptible vaginal yeast infections when used according to the recommended regimen.
Dosage and Administration: The usual adult regimen for clotrimazole 100 mg vaginal tablets is one tablet inserted deeply into the vagina at bedtime for six consecutive nights. Other regimens may be approved depending on the product formulation and local labeling. Follow the approved CLOTRILIN package leaflet or the healthcare professional's instructions. The tablet is for vaginal use only and must not be swallowed.
Method of Administration: Wash hands before and after administration. Insert the vaginal tablet according to the package instructions, preferably at bedtime. Complete the prescribed treatment course, even if symptoms improve earlier. Avoid contact with the eyes and do not use the product by mouth.
Use During Pregnancy: Clotrimazole vaginal treatment may be used during pregnancy when clinically indicated and under healthcare professional supervision. During pregnancy, vaginal tablets are generally inserted without an applicator to minimize the risk of mechanical injury.
Breastfeeding: Because vaginal administration results in low systemic absorption, clotrimazole is generally considered compatible with breastfeeding. Consult a healthcare professional if symptoms persist or additional treatment is required.
Drug Interactions: Clinically significant systemic interactions are uncommon with vaginal administration. Patients using tacrolimus or sirolimus should consult their healthcare professional because clotrimazole may affect drug exposure in certain circumstances. Some vaginal products may also affect latex condoms or diaphragms; check the product leaflet for specific precautions.
Possible Side Effects: Local adverse effects may include vaginal burning, itching, redness, irritation, discomfort, or mild abdominal cramping. These effects are usually localized. Stop treatment and seek medical advice if severe irritation, swelling, rash, breathing difficulty, or other signs of a serious allergic reaction develop.
Contraindications: CLOTRILIN should not be used in patients with known hypersensitivity to clotrimazole or any ingredient in the formulation.
Warnings and Precautions: Seek medical advice before treatment if this is the first episode of vaginal symptoms, the diagnosis is uncertain, or symptoms recur frequently. Medical evaluation is recommended for fever, lower abdominal pain, foul-smelling discharge, vaginal bleeding, sores, or pain during urination. Consult a healthcare professional if symptoms do not improve after treatment or worsen during use.
Patient Counseling: Use only as directed. Avoid vaginal douching and other intravaginal products during treatment unless advised by a healthcare professional. Menstruation may affect treatment in some circumstances; follow the product leaflet or professional advice. Avoid relying on latex condoms or diaphragms during the period specified in the product instructions.
Storage: Store according to the approved packaging instructions, protect from moisture when required, and keep out of reach of children.
Product Summary: CLOTRILIN 100 mg Vaginal Tablet provides localized clotrimazole antifungal therapy for susceptible vaginal yeast infections, helping control fungal growth and relieve associated discomfort when used according to approved directions.
Company: LINCOLN