CEFALIN 400 mg CAPSULE
Active Ingredient: Cefixime 400 mg
Family: Cephalosporin Antibiotic (Third Generation)
Dosage Form: Capsule
Strength: Each capsule contains Cefixime 400 mg.
Product Description: CEFALIN 400 mg is an oral antibiotic containing cefixime, a third-generation cephalosporin with bactericidal activity against susceptible bacteria. It works by inhibiting bacterial cell-wall synthesis, helping eliminate susceptible bacterial pathogens and control bacterial infections.
Indications: CEFALIN 400 mg is indicated for the treatment of selected bacterial infections caused by susceptible organisms, including uncomplicated urinary tract infections, pharyngitis, tonsillitis, and certain acute exacerbations of chronic bronchitis. The appropriate indication depends on bacterial susceptibility, clinical assessment, and locally approved product labeling.
Mechanism of Action: Cefixime binds to specific penicillin-binding proteins and inhibits the final stages of bacterial cell-wall synthesis. This weakens the bacterial cell wall and leads to bacterial cell death. Its antibacterial activity depends on the susceptibility of the causative organism.
Clinical Benefits: CEFALIN provides systemic antibacterial treatment against susceptible pathogens. It helps control bacterial infections, supports clinical recovery, and offers convenient oral administration. Its third-generation cephalosporin activity makes it a useful treatment option for selected infections when clinically appropriate.
Key Benefits: Broad activity against a range of susceptible Gram-positive and Gram-negative bacteria; convenient oral capsule administration; established antibacterial mechanism; and once-daily administration for many adult treatment regimens when prescribed appropriately.
Dosage and Administration: The usual adult dose is 400 mg once daily, depending on the type and severity of infection. Treatment duration is determined by the prescribing healthcare professional and the specific infection. The capsule may generally be taken with or without food. Take it with water and complete the prescribed course. Do not use antibiotics without an appropriate prescription.
Pediatric Use: Pediatric dosing is generally weight-based and depends on age, formulation, infection, and clinical condition. The 400 mg capsule should not automatically be used in children. A healthcare professional should select an appropriate formulation and dose.
Use During Pregnancy: Cefixime should be used during pregnancy only when considered necessary by a healthcare professional after assessing the expected benefits and potential risks.
Breastfeeding: Consult a healthcare professional before using cefixime during breastfeeding. The decision should consider the mother's clinical needs and the potential for effects in the nursing infant.
Drug Interactions: Cefixime may increase carbamazepine concentrations in some patients. Concomitant use with warfarin or other anticoagulants may increase prothrombin time and bleeding risk. Inform the prescribing healthcare professional about all medicines and supplements being used.
Possible Side Effects: Common adverse effects include diarrhea, nausea, abdominal pain, loose stools, indigestion, and vomiting. Less commonly, allergic reactions or severe antibiotic-associated diarrhea may occur. Seek urgent medical attention for difficulty breathing, facial or throat swelling, or a severe allergic reaction. Persistent or severe diarrhea requires medical evaluation.
Contraindications: Do not use in patients with known hypersensitivity to cefixime or other cephalosporin antibiotics. Patients with a history of severe reactions to penicillins or other beta-lactam antibiotics should inform their healthcare professional before treatment.
Warnings and Precautions: Use cefixime only for bacterial infections that are proven or strongly suspected to be caused by susceptible organisms. It is not effective against viral infections such as influenza or the common cold. Use cautiously in patients with kidney impairment, significant gastrointestinal disease, or a history of antibiotic-associated colitis. Dose adjustment may be necessary in renal impairment. Unnecessary antibiotic use can contribute to antimicrobial resistance.
Product Summary: CEFALIN 400 mg Capsule is a third-generation cephalosporin antibiotic formulated for oral administration. It offers convenient treatment for selected susceptible bacterial infections through inhibition of bacterial cell-wall synthesis and should be used according to the approved product information and healthcare professional's instructions.
Company: LINCOLN