VIVIAN INJECTION 75 mg
Active Ingredient: Diclofenac Sodium 75 mg
Family: Non-Steroidal Anti-Inflammatory Drug (NSAID)
Dosage Form: Solution for Injection
Strength: Each ampoule contains Diclofenac Sodium 75 mg. Confirm the ampoule volume and concentration against the approved product packaging.
Product Description: VIVIAN Injection contains diclofenac sodium, a potent non-steroidal anti-inflammatory agent with analgesic and anti-inflammatory properties. It is used for the short-term management of acute pain and inflammatory conditions when injectable treatment is clinically appropriate.
Indications: VIVIAN Injection is indicated for the short-term treatment of acute moderate pain and inflammation, including acute musculoskeletal pain, postoperative pain, acute back pain, painful exacerbations of inflammatory joint disorders, acute gout attacks, and renal colic when appropriate. Use depends on the clinical assessment and approved product labeling.
Mechanism of Action: Diclofenac inhibits cyclooxygenase (COX) enzymes, reducing the synthesis of prostaglandins involved in pain, inflammation, and fever. This action helps reduce pain intensity, inflammatory swelling, and tenderness.
Clinical Benefits: VIVIAN Injection provides systemic pain relief and anti-inflammatory activity for selected acute conditions. Its injectable formulation is useful when rapid treatment is required or oral administration is unsuitable. Treatment should use the lowest effective dose for the shortest necessary duration.
Key Benefits: Helps relieve acute pain, reduces inflammation and tenderness, supports improved mobility during painful musculoskeletal episodes, and provides an injectable option for short-term pain management under professional supervision.
Dosage and Administration: For adults, a commonly used dose is 75 mg by deep intramuscular injection. A further dose may be considered by a healthcare professional when clinically necessary. The total diclofenac dose from all formulations should generally not exceed 150 mg in 24 hours. Injectable treatment is usually limited to a maximum of two days. The exact regimen must follow the approved product leaflet and the patient's clinical condition.
Route of Administration: Administer only by the route specified in the approved product instructions. Deep intramuscular injection must be performed by a qualified healthcare professional to reduce the risk of nerve and tissue injury. Intravenous administration is permitted only if the specific formulation is approved for that route and must follow its required dilution and infusion instructions. Never administer by an unapproved route.
Contraindications: Do not use in patients with known hypersensitivity to diclofenac or other NSAIDs; previous aspirin- or NSAID-induced asthma or allergic reactions; active or recurrent peptic ulcer, gastrointestinal bleeding, or perforation; severe renal or hepatic impairment; established significant cardiovascular disease where diclofenac is contraindicated; or active bleeding, according to the approved product information.
Possible Side Effects: Common adverse effects include nausea, vomiting, abdominal pain, indigestion, and injection-site pain or reactions. Other possible effects include dizziness, fluid retention, increased blood pressure, and changes in kidney or liver function. Serious risks include gastrointestinal bleeding, severe allergic reactions, cardiovascular events, and kidney injury. Seek urgent medical attention for chest pain, difficulty breathing, facial swelling, black stools, or vomiting blood.
Drug Interactions: Concomitant use with other NSAIDs, including ibuprofen or naproxen, may increase adverse effects. Anticoagulants and antiplatelet agents may increase bleeding risk. Corticosteroids and certain antidepressants may also increase gastrointestinal bleeding risk. Diclofenac may interact with lithium, digoxin, methotrexate, ciclosporin, tacrolimus, diuretics, ACE inhibitors, and angiotensin receptor blockers. Inform the healthcare professional about all medicines being used.
Use During Pregnancy: Diclofenac should generally be avoided during pregnancy unless specifically prescribed after medical assessment. It may cause fetal complications from approximately 20 weeks of pregnancy onward, and it is contraindicated during the third trimester under standard product labeling. A healthcare professional should select an appropriate alternative when necessary.
Breastfeeding: Diclofenac use during breastfeeding should be assessed by a healthcare professional, considering the dose, duration, and product information. Do not self-administer injectable diclofenac while breastfeeding.
Warnings and Precautions: Use with particular caution in patients with hypertension, cardiovascular disease, asthma, a history of gastrointestinal ulcers, kidney or liver impairment, dehydration, or advanced age. Diclofenac may increase the risk of gastrointestinal bleeding, kidney injury, and cardiovascular complications. Do not combine it with another NSAID unless specifically instructed by a healthcare professional.
Storage: Store according to the approved product packaging instructions. Protect from unsuitable temperatures and keep out of reach of children. Do not use the injection if the solution is discolored, contains visible particles, or the ampoule is damaged.
Product Summary: VIVIAN Injection 75 mg is a diclofenac-based injectable analgesic and anti-inflammatory medicine designed for short-term management of selected acute painful and inflammatory conditions. Appropriate patient selection, professional administration, and adherence to approved dosing instructions are essential for safe and effective use.
Company: LINCOLN